endotoxins

A term used to describe an essential lipopolysaccharide (LPS) component of the cell wall of Gram-negative bacteria. Together with phospholipids and membrane-bound proteins it is a constituent of the outer cell membrane. These lipopolysaccharides define many of the properties of host-parasite interactions. The diversity of the bacterial lipopolysaccharides is responsible for the characteristic antigenic properties of Gram-negative bacteria. For a commonly used assay system of endotoxin see also: Limulus amoebocyte lysate assay.

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Entry last modified: February 2012