hemorphins

This term has been coined by Brantl et al (1986) for short opiod peptides derived from hemoglobin. These peptides are generated by enzymatic hydrolysis of the beta-chains, kappa-chains, delta-chains, or epsilon-chains of hemoglobin in vitro (Nyberg et al, 1997). They have been identified also as naturally occurring peptides in brain, plasma, and cerebrospinal fluid as well as extracts of normal adrenal tissue and pheochromocytoma tumors Cerpa-Poljak et al, 1997), lung tissues (Yatskin et al, 1998), and the bronchiolaval fluid of patients with non-small cell lung cancer (Duethman et al, 2000). Gelman JS et al (2010) have pointed out that many peptides derived from hemoglobin are found only in brain and not in blood, whereas all hemoglobin-derived ... ... ... ...
 
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Entry last modified: August 2017