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neurotractin

abbr. Ntra. This protein has been identified by Marg et al (1999). Neurotractin expression is restricted to subsets of developing commissural and longitudinal axon tracts in the chick central nervous system. Recombinant neurotractin promotes neurite outgrowth of telencephalic neurons and interacts with other members of the IgLON family of proteins such as CEPU-1 and LAMP (Marg et al, 1999).

Sequence analysis shows that Neurotractin is the chicken counterpart of Kilon. The approved gene symbol is NEGR1 [neuronal growth regulator 1]. The cDNA has been cloned independently as KIAA3001.

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