punt

gene symbol: put. Drosophila melanogaster punt (gene CG7904) encodes a transmembrane serine/threonine kinase. punt is essential in vivo for Drosophila melanogaster patterning processes depending upon the activity of dpp (decapentaplegic) (Letsou et al, 1995). Mutations in punt produce phenotypes similar to those exhibited by tkv (thickveins), sax (saxophone), and dpp mutants (Ruberte et al, 1995).

punt and the dpp receptor, tkv (thickveins) appear to act in concert to transduce the dpp signal. punt on its own binds Activin A but not BMP2 ... ... ... ...
 
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Entry last modified: January 2006