spinous cells |
spinster homolog 1 |
Oxyntomodulin-(30-35) |
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This Drosophila melanogaster gene (gene CG8428; symbol spn, spin) has been identified initially in a project designed to identify behavioural mutations. Mutations in the spinster gene are characterized by an extraordinarily strong rejection behavior of female flies in response to mafle courtship. Mutated flies are also characterized by decreases in viability, adult life span, and oviposition rate of the flies (Nakano et al, 2001).
In spin mutants, some oocytes and adult neural cells undergo degeneration, which is preceded by reductions in programmed cell death of nurse cells in ovaries and of neurons
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