Ontak |
oocyte-secreted protein-1 |
lutein-stimulating hormone |
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[oocyte]
These cells are the female egg cells (see also: germ cells). Primary oocytes are diploid cells generated before birth. Secondary oocytes are haploid cells generated after birth during ovulation.
The development and function of oocytes largely depends on cooperativity with supporting cells such as cumulus cells and granulosa cells. Oocytes play an active role in this cooperativity by secreting factors that act on the supporting cells in a paracrine manner (Sugiura and Eppig, 2005).
The differentiation of oocytes begins with the division germline stem cells
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