uPAR(88-92) |
upd |
Properdin(143-161) |
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[Urokinase receptor-associated protein] In the nomenclature of CD antigens this protein has been given the designation CD280.
This protein has been identified as a member of a trimolceular complex comprising urokinase receptor and pro-urokinase. cDNA cloning shows that uPARAP is a member of the macrophage mannose receptor protein family and contains a putative collagen-binding domain (fibronectin type 2) in addition to 8 C-type carbohydrate recognition domains. The protein binds strongly to collagen type 5 (Behrendt et al, 2000).
uPARAP is present on fibroblasts, macrophages and a subset of
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