3CH134

An early response gene the transcription of which in fibroblasts is rapidly and transiently stimulated by serum growth factors (Charles et al, 1992). Expression is increased up to 40-fold in fibroblasts exposed to oxidative/heat stress and growth factors.

3CH134 encodes a protein of 367 amino acids with the activity of a tyrosine phosphatase (Charles et al, 1993).

Mouse 3CH134 is a homolog of human CL100. These genes are related closely to erp (externally regulated phosphatase) and Vaccinia virus protein phosphatase VH1. The rat homolog of 3CH134 has been identified as ... ... ... ...
 
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Entry last modified: March 2012