AIP56
[apoptosis inducing protein 56 kDa] This protein is encoded by a plasmid of Photobacterium damselae subsp. piscicida (Phdp), the agent of the widespread fish pasteurellosis. The plasmid-encoded protein is an exotoxin abundantly secreted by all virulent, but not avirulent, Phdp strains and induces cell death by apoptosis of sea bass macrophages and neutrophils. Passive immunization of sea bass with a rabbit anti-AIP56 serum confers protection against Phdp challenge (do Vale et al, 2005).
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia. For other relevant entries see also the
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