AUH
[AU RNA binding protein/enoyl-CoA hydratase; AU-binding protein/enoyl-CoA hydratase, AU-specific RNA-binding enoyl-CoA hydratase] This RNA-binding protein has been identified by Nakagawa et al (1995), using a matrix of AUUUA similar to the AU-rich elements found in the 3-prime untranslated region of many short-lived mRNAs. In vitro, the recombinant protein binds specifically to AU-rich transcripts, including those for IL3, GM-CSF, fos, and myc.
The protein has been shown to have the activity of Methylglutaconyl-CoA hydratase (3-methylglutaconyl-CoA hydratase), one of the key enzymes of leucine degradation. Ly et al (2003) have reported that
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