CD177
[CD177(+), CD177(-)]
Other designations:
HNA2A [human neutrophil antigen 2a]
NB1
NB1 gp [NB1 glycoprotein]
Neutrophil-specific antigen 1
PRV1 [polycythemia rubra vera 1]
This antigen appears to be expressed only on a subpopulation of neutrophils (for references see entries: PRV1, NB1).
The function of CD177 is not known. Reduced expression of CD177 has been observed in granulocytes from patients with paroxysmal nocturnal haemoglobinuria (Bux et al, 1992). Complete lack of expression of CD177 on neutrophils
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