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CFU-F

[colony-forming unit fibroblast; colony-forming unit fibroblastoid; fibroblast colony-forming cells; fibroblast colony-forming units] This term refers to a population of adherent cells from the bone marrow grown in culture (see also: colony formation assay, BMC). These bone marrow stromal cells and are non-phagocytic, have an appearance resembling that of fibroblasts (Friedenstein et al, 1970, 1974; Xu et al, 1983). Apart from typical fibroblast features these cells are distinct from endothelial cells or macrophages (Castro-Malaspina et al, 1980; Fei et al, 1990; Song and Quesenberry, 1984; Zhang et al, 1995).

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Entry last modified: August 2013



 
 
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