DNA methylation

see: gene expression.

The term DNA methylation refers to the addition of a methyl group to the carbon 5 of cytosine, which yields 5-Methyl-Cytosine. The transfer of the methyl group from S-adenyl methionine to the cytosine residue is catalyzed by a family of DNA methyltransferases, some of which establish a new methylation pattern to unmodified DNA (see, for example: DNMT3B [DNA methyltransferase 3B]), while others copy the DNA methylation pattern of a DNA during DNA replication. DNA methylation mostly occurs in cytosine residues that precede a guanine nucleotide (CpG dinucleotide) and can occur in the promoter of a gene, in exons ... ... ... ...
 
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Entry last modified: December 2022