FGP cells |
fgr |
G-protein-coupled receptor CY4 |
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This peptide has been identified by phage display methods. It acts as a cell-targeting peptide and, binds selectively to human neutrophils, inducing a pertussis toxin-sensitive increase in cytosolic calcium analogous to that observed with G-alpha(i)-coupled receptors (Mazzucchelli et al, 1999; Jaye et al, 2001, 2003).
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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