GIF |
GIFB |
Semaphorin L |
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[Growth inhibitory factor] This biochemically uncharacterized 25 kDa factor is secreted by macrophages in murine lung tissues and bone marrow (Ikuta et al, 1989: Kasukabe et al, 1988). This factor inhibits the growth of murine monocytic leukemia cell lines (Mm-A, J774). The human monocytic leukemia cell lines U937 and THP-1 and the promyelocytic cell line HL-60 do not respond to this factor. The factor also inhibits the growth of murine bone marrow cells stimulated by M-CSF.
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