IFNs

abbr. for interferons. By definition interferons are proteins that, at least in homologous cells, elicit a virus-unspecific antiviral activity. This activity requires new synthesis of RNA and proteins and is not observed in the presence of suitable RNA and protein synthesis inhibitors.

Apart from their antiviral activities interferons also possess antiproliferative and immunomodulating activities and influence the metabolism, growth and differentiation of cells in many different ways.

General actions and activities of interferons

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Entry last modified: January 2004

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