L-DC |
LDCs |
CCP module-containing protein 22 |
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[lymphocyte-derived chemotactic factor] This protein is produced by antigen- and mitogen-stimulated CD4(+) lymphocytes. It is encoded by the JE gene and has a length of 76 amino acids (12.5 kDa). LDCF therefore belongs to the family of chemotactic cytokines known as Chemokines (subgroup of CC-Chemokines). The new designation is CCL2. See also: SCY family of cytokines.
LDCF is identical with MCP-1 (monocyte chemoattractant protein-1), MCP (monocyte chemotactic protein), MCAF (monocyte chemotactic and activating factor), HC11, SMC-CF (
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