LIGHT

[an acronym derived from homologous to lymphotoxins, inducible expression, competes with HSV glycoprotein D for HVEM, a receptor expressed on T-lymphocytes].

LIGHT is a member of the TNF cytokine family. Based on its homology with other members of the TNF ligand protein superfamily the protein is referred to also as TNFSF14 [TNF ligand superfamily member 14] and is identical with HVEM ligand (HVEM-L). In the nomenclature of CD antigens it has been given the designation CD258.

The gene was isolated from a cDNA library prepared from activated ... ... ... ...
 
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Entry last modified: January 2006