MNPLAQPVIY |
MNSF-beta |
NAP-IF |
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[monoclonal nonspecific suppressor factor] This factor of 12 kDa is produced by a murine T-cell hybridoma E17 stimulated with concanavalin A (Nakamura et al, 1986, 1987).
The N-terminal amino acid sequence of the protein shows significant (60 %) homology to transforming growth factor TGF-beta-2 (Nakamura et al, 1992). A similar human factor, designated hNSF (see: NSF), is produced by concanavalin A-stimulated CD8(+) T-cells (Xavier et al, 1995).
The cDNA clone encoding MNSF-beta (a subunit of MNSF; Nakamura et al, 1995) is virtually identical with the Fau protein
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