MS4A1 |
MS4A2-trunc |
TRADE-alpha |
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(approved gene symbol) [Membrane-spanning 4-domains subfamily A2]. The protein is encoded by the FCER1B [High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; Fc epsilon receptor 1 beta-chain; Fc-epsilon-R1-beta] gene, which encodes the beta subunit of the FcIgE receptor. The gene has been cloned by Kuster et al, 1992).
A splice variant expressed in lung mast cells, termed MS4A2-trunc, has been described by Cruse et al (2010). Its expression is negatively regulated by stem cell factor SCF, the ligand for the kit oncogene
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