Monokine induced by gamma-Interferon |
monolayer |
FXIIa |
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[monokine]
This is a generic name for a number of unrelated soluble proteins produced by cultured macrophages and monocytes following cell activation or damage.
GM-CSF, IL1, IL10, IL15, IL18, IL6, IL8, mig, TNF-alpha, for example, are some monokines. The nomenclature is problematic, however, since it was shown that these factors are not secreted exclusively by monocytes (see also: Cytokines; for some personal views of problems associated with nomenclature see also: Some personal remarks).
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