cytokines

The term cytokine, or immunocytokines, was used initially to separate a group of immunomodulatory proteins, called also immunotransmitters, from other growth factors or regulatory peptide factors that modulate the proliferation and bioactivities of non-immune cells. This terminology suggested a clear-cut distinction and could not be maintained and may not be meaningful altogether. Some cytokines are indeed produced by a rather limited number of different cell types, whereas others are produced by almost the entire spectrum of known cell types.

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Entry last modified: January 2023