NKIR |
NKL |
gas-5 |
||
[immunoregulatory NK-cells] This cell type constitutes a subpopulation of NK-cells (Giuliani et al, 2008). In contrast to normal NK-cells, which are considered traditionally to be major innate effector cells and are cytotoxic for virus-infected cells or tumor cells, NK-ireg cells are non-cytolytic. Cells of this subset are characterized by their mature phenotype and the cell surface expression and/or release of the immunosuppressive protein HLA-G.
NK-ireg cells have been shown to express CD56, CD16, NKp30, NKp44, NKp46, CD94, CD69, and CCR7
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |