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PGIF

[liver purified growth inhibitory factor] This factor of 37 kDa was isolated from liver lysates of adult hamsters. It inhibits the growth of SV40-transformed hamster fibroblasts in culture. cause reversible arrest of the transformed fibroblasts predominantly in the G0/G1 phase of the cell cycle. The activity is not found in lysates from the liver of fetal or 7-day-old hamsters.

The murine cDNA isolated from a mouse liver cDNA library encodes a protein of 323 amino acids that shares high homology with rat and human liver arginases (92 % and 93 % identity with rat arginase ... ... ... ...
 
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Entry last modified: March 2020



 
 
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