PL(A2) |
PLAC1 |
T-cell growth factor-beta |
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[Placental bone morphogenetic protein] Human PLAB (308 amino acids) is a member of the BMP (Bone morphogenetic proteins) protein family expressed highly in placenta (Hromas et al, 1997). The protein sequence of PLAB is most closely related to BMP8. The protein is identical with PDF (prostate-derived factor), MIC1 (macrophage inhibitory cytokine-1), GDF15 (growth/differentiation factor-15), and PTGF-beta. It has been described independently as NAG-1 [NSAID activated gene-1] and PL74.
PLAB has been shown to inhibit the proliferation of
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