MIA SH3 domain containing |
MIC2 |
defensin-beta-8 |
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[macrophage inhibitory cytokine-1] This gene was isolated in a subtraction cloning approach (see also: gene library) designed to identify genes expressed in association with the cell activation of macrophages.
MIC1 encodes a protein with structural characteristics of cytokines belonging to the TGF-beta superfamily but it has no strong homology to family members already known (Bootcov et al, 1997). The protein is identical with PDF (prostate-derived factor) and with PLAB (Placental bone morphogenetic protein), and PTGF-beta. The protein has been identified independently as PL74 and NAG-1 [
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