protein related to DAN and cerberus |
protein S-alpha |
Heparin binding growth factor-beta |
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Approved gene symbol: PROS1. Protein S is a secreted vitamin K-dependent gamma-carboxylated protein (called also Vitamin K-dependent protein S) that is synthesized mainly in the liver (Ploos van Amstel et al, 1988). Plasma contains a free, functionally active form, and an inactive form complexed with C4b-binding protein (Dahlback, 1991; Dahlback and Stenflo, 1981). The cDNA encoding human protein S has been cloned by Lundwall et al (1986) and Hoskins et al (1987). Ploos van Amstel et al (1987) have reported the existence of two highly homologous protein S genes, termed PSA [PS-alpha; protein S-alpha] and PSB [
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