S-cells |
scERV1 |
ASYIP |
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[stem cell expansion promoting factor] This biochemically poorly characterised activity was observed in studies using the stromal cell line AC6.21 for ex vivo expansion of transplantable human hematopoietic stem cells (Shi et al, 2000).
SCEPF activity is found in the conditioned medium of AC6.21 cells treated with LIF. This activity is not due to IL3, IL6, GM-CSF, SCF, flt-3 ligand, or thrombopoietin.
It is not known if SCEPF activity is mediated by a single factor or by multiple growth factors.
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