SCUBE2
[Signal peptide-CUB-EGF-like domain containing protein 2] SCUBE2, referred to also as (CEGP1 [CUB and EGF-like domain-containing protein 1] CEGB1, or CEGF1, is expressed in endothelial cells from various highly vascularized tissues (Yang et al, 2002) and other cell types such as fibroblasts and renal mesangial cells. The protein can form a heteromeric complex with SCUBE1.
Grimmond et al (2001) have reported that SCUBE2 gene expression is restricted to the embryonic neuroectoderm but is detectable also in adult heart, lung and testis.
The zebrafish ortholog of SCUBE2, termed
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