SETA

[SH3 domain-containing gene expressed in tumorigenic astrocytes] SETA is an adaptor protein that contains a SH3 domain. The approved gene symbol is SH3KBP1 [SH3 domain kinase binding protein 1]. Take et al (2000) have cloned the gene encoding SETA as CIN85 [Cbl-interacting protein 85 kDa], which encodes a protein that interacts with the c-cbl oncogene that is known to play a role in mediating the EGF receptor signaling cascade. In several databanks CD2BP3 [CD2-binding protein 3] is listed as an alternative designation for SETA / CIN85 (for CD2 ... ... ... ...
 
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Entry last modified: November 2023