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ST-1

This term has multiple meanings:


(-1-) This human stromal cell line (see also: hematopoiesis) has been obtained from adherent fetal liver cell layers of Dexter-type long-term BMC (bone marrow culture). The cells have been established by spontaneous immortalisation without using SV40 (Tsai et al, 1986).

The cells have been shown to express M-CSF, IL6 mRNA, and undefined factors stimulating immature hematopoietic progenitors BFU-E, CFU-GM, CFU-G, and CFU-M. The cells do not produce IL3. Upon treatment with IL1 ... ... ... ...
 
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