STRL33 |
stromal barrier cells |
HMWK-kallikrein factor |
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[STRO-1(+), STRO-1(-)]
[stromal precursor antigen 1] an antigen recognized by a monoclonal antibody of the same name identified by Simmons and Torok-Storb (1991).
STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95 % of which are nucleated erythroid precursors. It does not react with committed progenitor cells (CFU-GM, BFU-E, CFU-Mix). Fibroblast colony-forming units (CFU-F) are present exclusively in the STRO-1(+) population, and this population can be enriched by selecting for cells expressing STRO-1 and glycophorin A. Long-term bone marrow culture of STRO-1(+)
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