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nuclear transport sequence
nucleated red cells
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This general term refers to any eukaryotic cell type possessing a nucleus. Normally, cells possess one nucleus only and are thus mononucleated cells. Cells may lose their nucleus when they undergo cell death (see also: karyolysis). Cytoplasts are artificially enucleated cells such as those utilized, for example, in procedures to produce embryos by somatic cell nuclear transfer.
Human erythrocytes and reticulocytes have lost their nuclei in the course of normal development. In other species, erythrocytes do have a nucleus. The terms polykaryocytes or multinucleated cells describes cells containing many nuclei as the result of altered cell cycle control mechanisms. Such cells may be generated in the course of normal development (e.g, osteoclasts, myotubes, and multinucleated giant cells contain many nuclei), or may represent an aberrant cell type. For examples see: syncytial cells, Warthin-Finkeldey cells.
For other related/relevant entries see also: Cell types.
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ENTRY LAST MODIFIED: January 2009
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