VCP

[vaccinia virus complement control protein] VCP (243 amino acids) (Vaccinia virus C21L protein) is encoded by the C21L gene in the genome of vaccinia virus. The gene shows homology to a group of eukaryotic genes encoding regulators of complement activation. A cowpox homolog of VCP is IMP. Another name is vC4bBP [viral C4b binding protein].

VCP is found in the conditioned medium of cells infected with vaccinia virus (Kotwal et al, 1990; Kotwal and Moss, 1988).

VCP can be expressed on the membrane of mammalian cells and then effectively protects the cells ... ... ... ...
 
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Entry last modified: January 2005