MICE |
microaposome |
ANGPTL2 |
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This gene (also simply referred to as mx gene) has been identified in the genome of the malaria vector Anopheles gambiae (Zhou et al, 2005). The protein is an antagonist of inhibitor of apoptosis proteins (see: IAP). Expression of the protein induces rapid cell death in insect cell lines and is a potent tissue ablator in vivo. Its pro-apoptotic activity is totally dependent on the presence of an IAP binding motif. Like reaper in Drosophila melanogaster, Mx is transcriptionally induced by ultraviolet irradiation to mediate cell death.
Liu B et al (2011) have reported that michelob_x(mx) expression is induced in mosquito laval midgut cells
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