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pentagastrin

This pentapeptide corresponds to the 5 C-terminal amino acids of the hormone gastrin and has many of the hormonal activities of gastrin. The peptide is identical with cholecystokinin-5 (CCK-5) and acts primarily by binding to the cholecystokinin type B receptor.

A synthetic pentapeptide (Boc-beta Ala-Trp-Met-Asp-Pheamide) that has the same biological effects as gastrin (Braganza et al, 1979) is used widely to stimulate gastric acid secretion in tests in man and in animals.

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