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Hepatocyte growth inhibitory factor
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A term used in older references describing shape forms of erythrocytes that deviate from standard forms (see also: discocytes).
Hildebrandt et al (1988) have observed these doughnut-shaped cells in urinary sediments of children with glomerular hematuria, but not in urinary sediments of children with non-glomerular hematuria. Bunyaratvej et al (1985) have observed torocytes in the blood of patients with beta-thalassemia/HbE disease. Their numbers are increased with anemia and after spleenctomy, whereas a larger spleen is associated with a decrease of these cell types.
For other entries pertaining to hematopoiesis see also the Hematology Dictionary section of this encyclopedia.
For other related/relevant entries see also: Cell types.
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ENTRY LAST MODIFIED: October 2006
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