A431

(ATCC CRL 1555) Human cell line established from an epidermoid carcinoma of the vulva of a 85 year old female patient.

A431 cells have been used for a variety of studies in cell biology. The cells grow into colonies when cultivated in soft agar (see also: Colony formation assay) or on lawns of human fibroblasts (see also: Feeder cells) and develop into subcutaneous tumors following subcutaneous injection into mice treated with antisera against thymocytes.

The conditioned medium of A431 cells contains a heparin binding protein, designated HBp17, which binds the ... ... ... ...
 
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Entry last modified: March 2002