AM binding protein-1 |
Amblyomma cajennense chemokine binding protein |
dendritic cell lectin |
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[Amblyomma Factor Xa inhibitor] This protein, a serine protease Kunitz-type inhibitor, has been identified in a cDNA library derived from the salivary glands of the tick Amblyomma cajennense (Batista et al, 2010). The recombinant mature protein inhibits Factor Xa (FXa) and extends global blood clotting times in vitro and ex vivo.
Action on apoptosis
Amblyomin-X has been shown to induce tumor mass regression and to reduce metastasis in a B16F10 murine melanoma model. Amblyomin-X selectively acts on tumor cells by inducing cell death by apoptosis
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