BLC |
BLCAP |
KIAA1624 |
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[B-lymphocyte cell adhesion molecule] Wilson et al (1991) have cloned a full-length cDNA for this B-cell membrane protein. The protein is known also as CD22. The full-length cDNA clone contains an open reading frame for a predicted protein of 847 amino acids (95 kDa). BLCAM has a predicted transmembrane spanning region and a 140-amino acid intracytoplasmic domain. The BLCAM cDNA is nearly identical to a CD22 cDNA, with the exception of an additional 531 bases in the coding region of BLCAM. BLCAM is a member of the immunoglobulin superfamily. It shows significant homology with three homotypic cell adhesion proteins: carcinoembryonic antigen
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