califins |
CALLA(+) cells |
non-cell-autonomous necrosis |
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[common acute lymphocytic leukemia antigen; common ALL antigen]. This antigen has been identified originally as a 100 kDa cell surface glycoprotein of unknown function on most acute lymphoblastic leukemias (Greaves et al, 1975; Ritz et al, 1980). The antigen is expressed also on lymphoblastic lymphomas, Burkitt lymphomas, and nodular poorly differentiated lymphocytic lymphomas as well as chronic myelogenous leukemias in lymphoid blast crisis (Greaves et al, 1983). CALLA is not a tumor-specific antigen as demonstrated by its identification on early lymphoid progenitor cells within bone marrow and fetal liver (Greaves et al, 1983; Hokland et al, 1983, 1984) and fetal thymocytes
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