CLA |
CLAGRLDKQCTCRRSQPSRRSGHEVGRPSPHCGPSRQCGCHMD |
CG1130 |
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[Corpus luteum angiogenic factor] This factor possesses the ability to augment new blood vessel formation (see: Angiogenesis). It is an aminoterminally truncated form of brain fibroblast growth factor bFGF.
The biological activity of CLAF is indistinguishable from that of pituitary FGF or brain FGF. It is highly mitogenic for cultured bovine vascular endothelial cells. CLAF also stimulates the proliferation of a wide variety of mesoderm- and neuroectoderm-derived cells, including vascular smooth muscle cells, granulosa and adrenal cortex cells, rabbit costal chondrocytes, and corneal
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