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mitogen

any agent, e.g., growth factors or cytokines, but also low-molecular weight substances, that promotes cell division (mitosis; see: cell cycle) and induces the proliferation of cells (mitogenesis). A widely used assay to detect mitogenic activity is the MTT assay. Frequently, the incorporation of bromodeoxyuridine (5-bromodeoxyuridine; BrdU). is used to measure cell proliferation.

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