FIC

[Fibroblast-inducible cytokine] FIC is the product of an immediate-early gene (see also: gene expression, early response genes), designated P16, isolated by differential screening of a cDNA library of serum-stimulated murine 3T3 fibroblasts.

FIC is a non-glycosylated monocytic cytokine of 97 amino acids. It displays 57 % homology to human and rabbit monocyte chemoattractant protein-1 (see: MCP-1).

FIC belongs to the family of chemotactic cytokines known as Chemokines /subgroup of ... ... ... ...
 
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Entry last modified: January 2002