glial cells |
Glial-derived neurite promoting factor |
CRF2-alpha receptor |
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abbr. GSF (a term with multiple meanings). This biochemically uncharacterized factor of 10-30 kDa is produced by T-lymphocytes and some T-cell lines (MOLT-4F, RPMI 1788). It stimulates RNA and DNA synthesis in cultured murine glia cells and influences the functional activities of progenitors of astrocytes. The GSF activity can be separated from other factors with macrophage inhibiting factor (MIF) and leukocyte migration inhibiting factor (MIF) activities, as well as mitogenic factor (MF) and lymphocyte
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