i-dNK-cells |
IDR-1002 |
IGF binding protein-10 |
||
[innate defense regulator peptide 1] This peptide (KSRIVPAIPVSLLamide) designed on the bases of LL-37 and other cationic host defense peptides, is an innate immune defense regulator that has been shown to be protective in murine models of infection with Gram-positive bacteria and Gram-negative pathogens, despite its complete lack of antimicrobial activity (Scott et al, 2007). Monocytes and macrophages, but not neutrophils or lymphocytes, play a key role for protection. IDR-1, like LL-37, enhances the levels of chemokines while reducing pro-inflammatory cytokine
... ... ... ...
... CONTINUE READING at cells-talk.com,
COPE's new home with 61 100+ entries, 141 552 cited references and >2,5
million internal hyperlinks. This most comprehensive knowledge base provides
extensive in-context information covering nomenclature, terminology, and
highlighting concepts, strategies & complexities of cellular communication
processes. COPE's fully integrated subdictionaries include
Dictionary of Angiogenesis •
Dictionary of Antimicrobial & host defense peptides •
Dictionary of Apoptosis and cell death •
Dictionary of CD antigens •
Dictionary of Chemokines •
Dictionary of Cryptides •
Dictionary of Cytokines & Growth factors •
Dictionary of Eukaryotic cell types & expression profiles •
Dictionary of Hematopoiesis •
Dictionary of Hormones •
Dictionary of Inflamation & inflammatory mediators •
Dictionary of Innate Immunity •
Dictionary of Metalloproteinases •
Dictionary of Moonlighting proteins & cryptides •
Dictionary of Neuropeptides •
Dictionary of Pathogenicity & Virulence Factors •
Dictionary of Pattern recognition receptors •
Dictionary of Protein domains •
Dictionary of Regulatory peptide factors •
Dictionary of Viroceptors •
Dictionary of Virokines •
Dictionary of Stem cells
and more.
An important note about your privacy: A search engine may have brought
you here. If the provided URL differs in any way from
"www.copewithcytokines.org/cope.cgi?key=search term", 3rd parties may
record your activities on COPE. Bypass snoopers by doing this: Go
directly to cells-talk.com or go to
copewithcytokines.org
in a new browser tab and from there explore whether COPE contains the terms
that interest you. The private bioinformatics initiative COPE at
cells-talk.com
never shares your search histories or user databank entry with 3rd parties.
SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
# | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R