ING2

[inhibitor of growth 2] This protein is known also as p33ING2 (Nagashima et al, 2001) or ING1L [ING1-like; inhibitor of growth 1-like] (Shimada et al, 1998). ING2 shares nearly 60 % sequence identity with ING1. The approved gene symbol is INGX.

Nagashima et al (2001) have reported that ING2 is a DNA damage-inducible gene that negatively regulates cell proliferation through activation of p53 by enhancing its acetylation. Okano et al (2006) have reported downregulated expression of ING2 in 6 of 7 lung cancer cell lines ... ... ... ...
 
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Entry last modified: March 2009