Leukocyte-derived 7-transmembrane domain receptor |
Leukocyte-derived neutrophil-activating peptide |
HCRTR2 |
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abbr. LDGF (a term with multiple meanings). This factor was described previously as MDGF (macrophage-derived growth factor) by Pencev and Grotendorst (1988) and has been renamed LDGF following the cloning of the gene and the observation that this factor is produced by neutrophils and T-lymphocytes. LDGF is the principal mitogen for fibroblasts produced by human macrophages in culture after cell activation with bacterial lipopolysaccharides (Iida et al, 1996).
LDGF has been found to be a precursor for a number of protein factors with the activity of
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