pEDVDHVFLRFamide |
pEEDCK |
Hb-Gower 1 |
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[pathogen-elicited epithelial chemoattractant] Production of this biochemically uncharacterized chemotactic factor (1-3 kDa) with the bioactivity of chemokines is observed after attachment of Salmonella typhimurium to T84 cell apical epithelial membranes (McCormick et al, 1998. The protein is released in a polarized apical fashion and is involved in the final step of transepithelial migration of neutrophils induced by Salmonella-apical membrane interaction. PEEC directly stimulates neutrophils via a pertussis toxin-sensitive receptor and elicits a calcium ion signal. PEEC elicits chemotactic
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