TFAR-19

[TF1 cell apoptosis-related gene-19] The approved gene symbol is PDCD5 [programmed cell death-5] (see).

This gene has been identified Liu et al (1999). TFAR-19 is expressed in a human premyeloid cell line established from a patient with erythroleukemia, TF-1, undergoing apoptosis after the withdrawal of GM-CSF from the culture medium. TFAR-19 encodes a protein of 125 amino acids. TFAR-19 is expressed ubiquitously Its expression is upregulated in tumor cells undergoing apoptosis. Expression of the protein enhances apoptosis triggered by the removal of growth factors or serum from ... ... ... ...
 
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Entry last modified: December 2004